#alkyne_zipper_reaction
Alkyne zipper reaction
The alkyne zipper reaction is an organic reaction that involves isomerization of a non terminal alkyne into a terminal alkyne. This reaction was first reported by Alexey Favorsky in 1887. Also, this reaction was reported by Charles Allen Brown and Ayako Yamashita in 1975. The isomerization reaction proceeds for straight-chain alkynes and acetylinic alcohols. The conversion provides a useful approach for remote functionalization in long-chain alkynes.
Thu 17th
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