Coding strand

DNA strand with the same base sequence as an mRNA transcript

When referring to DNA transcription, the coding strand is the DNA strand whose base sequence is identical to the base sequence of the RNA transcript produced. It is this strand which contains codons, while the non-coding strand contains anticodons. During transcription, RNA Pol II binds to the non-coding template strand, reads the anti-codons, and transcribes their sequence to synthesize an RNA transcript with complementary bases.

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