Keywords

#crizotinib

Crizotinib

ALK inhibitor for treatment of non-small-cell lung cancer

Crizotinib, sold under the brand name Xalkori among others, is an anti-cancer medication used for the treatment of non-small cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the oncogenesis of a number of other histological forms of malignant neoplasms. It also acts as an ALK and ROS1 inhibitor.

Mon 5th

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Crizotinib ALK positive lung cancer ALK inhibitor Lorlatinib Alectinib Beacon Pharmaceuticals ROS1 Inflammatory myofibroblastic tumour Non-small-cell lung cancer Carlo Gambacorti-Passerini
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