Cyclopia

Failure of the eye orbits to separate in two during embryonic development

Cyclopia, also known as alobar holoprosencephaly, is the most extreme form of holoprosencephaly and is a congenital disorder characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses.

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