#de_novo_mutation
De novo mutation
Genetic mutation not inherited from a parent
A de novo mutation (DNM) is any mutation or alteration in the genome of an individual organism that was not inherited from its parents. This type of mutation spontaneously occurs during the process of DNA replication during cell division. De novo mutations, by definition, are present in the affected individual but absent from both biological parents' genomes. These mutations can occur in any cell of the offspring, but those in the germ line can be passed on to the next generation.
Thu 28th
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