Desymmetrization

Molecular change in chemistry

Desymmetrization is a chemical reaction that converts prochiral substrates into chiral products. Desymmetrisations are so pervasive that they are rarely described as such except when they proceed enantioselectively. The enantioselective reactions require chiral catalysts or chiral reagents. According to IUPAC]], desymmetrization involves the "... the conversion of a prochiral molecular entity into a chiral one."

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