Keywords

#dihydrofolate_reductase

Dihydrofolate reductase

Mammalian protein found in humans

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as an electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in one-carbon transfer chemistry. In humans, the DHFR enzyme is encoded by the DHFR gene. It is found in the q14.1 region of chromosome 5.

Fri 23rd

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Dihydrofolate reductase Dihydrofolate reductase inhibitor Folinic acid Dihydrofolate reductase deficiency Trimethoprim Dihydrofolic acid Enzyme kinetics Folate Diaminopyrimidine Trimethoprim/sulfamethoxazole
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