Dimethyldioctadecylammonium bromide

Chemical compound

Dimethyldioctadecylammonium bromide is a double-chained quaternary ammonium surfactant that forms unilamellar vesicles (ULVs) in water. Among various preparation methods, the ‘‘hot-water” method offers a simple procedure to prepare DODAB cationic vesicles by simply dissolving the DODAB in hot water above 50 °C, i.e., chain melting (main) transition, Tm. In general, the DSC thermograms of the unsonicated DODAB dispersions are dominated by two endotherms; the pre- and main transition peaks. Moreover, in literature reported the presence of a third endotherm at 52.2 °C. The main transition (Tm) is ascribed to gel to liquid-crystalline phase transition in which the alkyl chains transform from solidlike to liquid-like state.

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