Heterophile antigen

Similar antigens present in different tissues and species

Heterophile antigens are antigens of similar nature, if not identical, that are present in different tissues in different biological species, classes, or kingdoms. Usually different species have different antigen sets, but the hetereophile antigen is shared by different species. Other heterophile antigens are responsible for some diagnostic serological tests such as:Weil-Felix reaction for typhus fever Paul Bunnell test for infectious mononucleosis Cold agglutinin test in primary atypical pneumonia

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