Keywords

#human_disease_modifier_gene

Human disease modifier gene

Type of modifier gene

A human disease modifier gene is a modifier gene that alters expression of a human gene at another locus that in turn causes a genetic disease. Whereas medical genetics has tended to distinguish between monogenic traits, governed by simple, Mendelian inheritance, and quantitative traits, with cumulative, multifactorial causes, increasing evidence suggests that human diseases exist on a continuous spectrum between the two.

Tue 5th

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Human disease modifier gene Stargardt disease CRISPR gene editing Coeliac disease Spinal muscular atrophy Alzheimer's disease Penetrance Oligogenic inheritance Autosomal dominant polycystic kidney disease Epistasis
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