Interstate 64

East–west Interstate in eastern US

Interstate 64 (I-64) is an east–west Interstate Highway in the Eastern United States. Its western terminus is at I-70, U.S. Route 40 (US 40), and US 61 in Wentzville, Missouri. Its eastern terminus is at the Bowers Hill Interchange with I-264 and I-664 at Bower's Hill in Chesapeake, Virginia. I-64 connects Greater St. Louis, the Louisville metropolitan area, the Lexington–Fayette metropolitan area, the Charleston metropolitan area, the Greater Richmond Region, and Hampton Roads.

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