#mirabamide
Mirabamide
Chemical compound
Mirabamides are sea sponge isolates that inhibit HIV-1 fusion. Variants A to D are known from Siliquariaspongia mirabilis and E through H are derived from Stelletta clavosa. Mirabamides have a macrocyclic region closed through an ester bond between the C-terminus and a 𝛽-hydroxyl group, and terminated with a polyketide moiety or a more simple branched aliphatic acid.
Thu 15th
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