Molecular tweezers

Molecules which bind other molecules

Molecular tweezers, and molecular clips, are host molecules with open cavities capable of binding guest molecules. The open cavity of the molecular tweezers may bind guests using non-covalent bonding, which includes hydrogen bonding, metal coordination, hydrophobic forces, van der Waals forces, π–π interactions, and/or electrostatic effects. These complexes are a subset of macrocyclic molecular receptors and their structure is that the two "arms" that bind the guest molecule between them are only connected at one end leading to a certain flexibility of these receptor molecules.

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