Keywords

#mutational_signatures

Mutational signatures

Mutational signatures are characteristic combinations of mutation types arising from specific mutagenesis processes such as DNA replication infidelity, exogenous and endogenous genotoxin exposures, defective DNA repair pathways, and DNA enzymatic editing.

Fri 8th

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Mutational signatures Tumor mutational burden Serena Nik-Zainal HRDetect Gene signature Ludmil Alexandrov Mutagen Mutation bias Aristolochia Mutation
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