Keywords

#n1-methylpseudouridine

N1-Methylpseudouridine

Chemical compound

N1-Methylpseudouridine is a natural archaeal tRNA component, and "hypermodified" pyrimidine nucleoside used in biochemistry and molecular biology for in vitro transcription and is found in the SARS-CoV-2 mRNA vaccines tozinameran (Pfizer–BioNTech) and elasomeran (Moderna).

Mon 2nd

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N1-Methylpseudouridine Self-amplifying RNA Pseudouridine T arm MRNA vaccine TRNA (pseudouridine54-N1)-methyltransferase Katalin Karikó Moderna COVID-19 vaccine Nucleoside-modified messenger RNA
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