#picropodophyllin

Picropodophyllin

Chemical compound

Picropodophyllin is a non-toxic small molecule inhibitor of the insulin-like growth factor-1 receptor (IGF1R). It is a stereoisomer of the molecule podophyllotoxin (PPT) which also acts as an inhibitor of the IGF1R. Both stereoisomers are classified as cyclolignans, with PPT being the trans conformation and picropodophyllin being the cis conformation.

Mon 12th

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