#protodeboronation
Protodeboronation
Protodeboronation, or protodeborylation is a chemical reaction involving the protonolysis of a boronic acid in which a carbon-boron bond is broken and replaced with a carbon-hydrogen bond. Protodeboronation is a well-known undesired side reaction, and frequently associated with metal-catalysed coupling reactions that utilise boronic acids. For a given boronic acid, the propensity to undergo protodeboronation is highly variable and dependent on various factors, such as the reaction conditions employed and the organic substituent of the boronic acid.
Tue 14th
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