Keywords

#s-adenosyl_methionine

S-Adenosyl methionine

Chemical compound found in all domains of life with largely unexplored effects

S-Adenosyl methionine (SAM), also known under the commercial names of SAMe, SAM-e, or AdoMet, is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. More than 40 methyl transfers from SAM are known, to various substrates such as nucleic acids, proteins, lipids and secondary metabolites. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. SAM was first discovered by Giulio Cantoni in 1952.

Tue 25th

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S-Adenosyl methionine S-Methylmethionine S-Adenosylmethionine synthetase enzyme S-Adenosyl-L-homocysteine Nicotinamide N-methyltransferase S-Adenosylmethioninamine Methionine S-methyltransferase Guanidinoacetate N-methyltransferase S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase S-adenosyl-L-methionine:xanthotoxol O-methyltransferase
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