#γ-aminobutyraldehyde

Γ-Aminobutyraldehyde

Metabolic intermediate

γ-Aminobutyraldehyde, also known as 4-aminobutanal or 4-aminobutyraldehyde, is a metabolite of putrescine and a biological precursor of γ-aminobutyric acid (GABA). It can be converted into GABA by the actions of diamine oxidase (DAO) and aminobutyraldehyde dehydrogenase (ABALDH). However, biosynthesis of GABA from polyamines like putrescine is a minor metabolic pathway in the brain. Monoacetylputrescine can be converted into ABAL via monoamine oxidase (MAO).

Mon 9th

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